造血干细胞抗原CD133抗体，Anti-CD133 antigen抗体

【产品名称】：造血干细胞抗原CD133抗体，Anti-CD133 antigen抗体

【产品类型】：一抗
【产品编号】：BYk-0395R

【相关标记】: HRP  Biotin  Gold  RBITC  AP  FITC  Cy3  Cy5  Cy5.5  Cy7  PE  PE-Cy3 PE-CY5  PE-CY5.5  PE-CY7  APC  Alexa Fluor 350  Alexa Fluor 488  Alexa Fluor 555 Alexa Fluor 647

【性 状】： Lyophilized or Liquid
【浓 度】： 1mg/1ml
【亚 型】： IgG

【规 格】：0.1ml/100ug，0.2ml/200ug
【抗体来源】： Rabbit OR MOUSE

【克隆类型】： polyclonal or monoclonal

【产品用途】：科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
【贮       存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【产品介绍】： Prominin is a novel plasma membrane protein with an N-terminal extracellular domain, five transmembrane segments flanking two short cytoplasmic loops ａnd two large glycosylated extracellular domains, ａnd a cytoplasmic C-terminal domain. DNA sequences from Caenorhabditis elegans predict the existence of a protein with the same features, suggesting that prominin is conserved between vertebrates ａnd invertebrates. Prominin is found not only in the neuroepithelium but also in various other epithelia of the mouse embryo. In the adult mouse, prominin has been detected in the brain ependymal layer, ａnd in kidney tubules. In these epithelia, prominin is specific to the apical surface, where it is selectively associated with microvilli ａnd microvilli-related structures. Remarkably, upon expression in CHO cells, prominin is preferentially localized to plasma membrane protrusions such as filopodia, lamellipodia, ａnd microspikes. These observations imply that prominin contains information to be targeted to, and/or retained in, plasma membrane protrusions rather than the planar cell surface. Moreover, results show that the mechanisms underlying targeting of membrane proteins to microvilli of epithelial cells ａnd to plasma membrane protrusions of non-epithelial cells are highly related.

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“造血干细胞抗原CD133抗体，Anti-CD133 antigen抗体”应用于IHC、WB、 IF、IP、ELISA，质量保证，无效免费退换，另外本公司生产经营ELISA试剂盒，生物试剂，细胞株，培养基，各种标记二抗、免疫印迹常用试剂、免疫组化常用试剂，欢迎来电咨询！