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Recombinant Human IL-4 Peprotech价格

产品信息
生长因子此类产品包括人、小鼠或大鼠的细胞外蛋白,多数情况下可启始或影响通过细胞表面受体传递的信号。下列产品包括人、小鼠和大鼠的白细胞介素、集落刺激因子、生长因子、干扰素、脂肪因子、BMP蛋白、FGFs、TNFs、可溶性受体、细胞外结合蛋白、非抑制型丝氨酸蛋白酶抑制剂及其他免疫调节蛋白等。
 Recombinant Human IL-4 Peprotech价格
产品编号:
200-04
别名:
BCGF,BCDF,B cell stimulating factor (BSF-1)
描述:
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
氨基酸序列:
MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
 
 
 
 
研究领域:
细胞凋亡 癌症
细胞培养 免疫系统
炎症 增殖
干细胞及分化 过敏
移植    
 
 
原产国:
USA
仅用于研究。不适用于诊断或ZL。

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