Recombinant CD44v4 Antibody

产品类型：
Primary antibody
纯化方法：
Purified
通用信息：
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide; *For IHC use only*
产品描述：
This antibody recognizes an epitope encoded by exon v4 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
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