16-phenyl tetranor Prostaglandin E2,7-[(2R)-3-hydroxy-2-(3-hydroxy-4-phenylbut-1-enyl)-5-oxocyclopentyl]hept-5-enoic acid,38315-44-5

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试剂描述：

产品名称：16-phenyl tetranor Prostaglandin E2

产品别名：7-[(2R)-3-hydroxy-2-(3-hydroxy-4-phenylbut-1-enyl)-5-oxocyclopentyl]hept-5-enoic acid

CAS号：38315-44-5

英文别名：7-[(2R)-3-hydroxy-2-(3-hydroxy-4-phenylbut-1-enyl)-5-oxocyclopentyl]hept-5-enoic acid

分子量：372.5

分子式：C₂₂H₂₈O₅

纯度：见爱必信官网

外观：见爱必信官网

保存方法：Store at -20° C

描述：16-phenyl tetranor PGE2 is a metabolically stable tissue selective synthetic analog of PGE2 , believed to be five times more potent than PGE2 in causing hypotension in dogs (0.1 μg/kg dose), and comparable to PGE2 in inhibiting histamine-induced bronchoconstriction in conscious guinea pigs. The increased stability toward metabolism can help to explain the increased potency due to a longer half-life in physiological conditions.

应用：An analog of PGE2 that is more potent in eliciting hypotension & bronchoconstriction

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