Osteoprotegerin / OPG Antibody (aa20-37, clone 98A1071)

分子量：
46kDa
细胞定位：
Antigen Cellular Localization:Secreted.
形式：
Liquid
参考文献：
Simonet W.S.,et al.Cell 89:309-319(1997).Yasuda H.,et al.Endocrinology 139:1329-1337(1998).Morinaga T.,et al.Eur. J. Biochem. 254:685-691(1998).Ota T.,et al.Nat. Genet. 36:40-45(2004).Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Osteoprotegerin / OPG antibody (aa20-37, clone 98A1071).
功能：
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
总结：
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
联系方式：

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京经济技术开发区永昌中路4号院4号楼3层