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Transcription factor E2F4 Antibody (internal region)

产品信息
  • 分子量:
    43960 Da
    细胞定位:
    Antigen Cellular Localization:Nucleus.
    形式:
    0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
    参考文献:
    Coordinated repression of cell cycle genes by KDM and E2F4 during differentiation. Beshiri ML, Holmes KB, Richter WF, Hess S, Islam AB, Yan Q, Plante L, Litovchick L, Gévry N, Lopez-Bigas N, Kaelin WG, Benevolenskaya EV. Proceedings of the National Academy of Sciences of the United States of America 2012 Nov 109 (45): 18499-504. PMID: 23093672
    产品概述:
    We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Transcription factor E2F4 antibody (internal region).
    功能:
    Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
    总结:

    联系方式:

    生物商城:http://www.annoron.com

    办公电话:010-56256916

    官方售后:400-965-8633

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