分子量：
28219 Da
细胞定位：
形式：
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
参考文献：
The expression of seven 14-3-3 isoforms in human meningioma. Liu Y, et al. Brain Res, 2010 Jun 8. PMID 20388496.Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin. Margariti A, et al. Circ Res, 2010 Apr 16. PMID 20224040.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets. Mangin PH, et al. J Thromb Haemost, 2009 Sep. PMID 19558434.Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein. Brummer T, et al. EMBO J, 2008 Sep 3. PMID 19172738.
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality YWHAH antibody (monoclonal) (M04).
功能：
总结：
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
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