Product Name CD150 antibody(PE conjugated)
Catalog No PAab09790
Packing 100ul
Form liquid
Alternative Name CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906
Purification Protein G purified
Purity 95% as determined by SDS-PAGE
Host Rat
Isotype IgG1
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM(signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembranemolecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells.The expression is upregulated upon activation. CD150 expression has been shown to bemaintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150.Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especiallywhen co-stimulated through the TCR. CD150 associates with the src homology2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to beinvolved in signal transduction. In combination with CD48, CD150 is a useful marker forhematopoieticstem cell studies.
Immunogen signaling lymphocytic activation molecule family member 1
Specificity Mouse
Tested Application FC
Recommended dilution 1：10-1：50
IHC use
WB use
Protein Information
Gene ID
Uniprot ID Q9QUM4
Calculated MW 11kd
Research Area
