Product Name P Glycoprotein antibody
Catalog No PAab09805
Packing 100ul
Form liquid
Alternative Name ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
Immunogen ABCB1
Specificity Human, Mouse
Tested Application ELISA, WB, IP, IHC
Recommended dilution WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500
IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09805(P glycoprotein antibody) at dilution of 1:500
WB use
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09805(P glycoprotein antibody) at dilution of 1:300
Protein Information
Gene ID
Uniprot ID P08183
Calculated MW 173 kDa
Research Area Neuroscience, Immunology, Metabolism
