Product Name Anti-Tyrosinase antibody
Catalog No PAab09856
Packing 100ul
Form liquid
Alternative Name ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Tyrosinase
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IHC, IF
Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
IHC use Immunohistochemistry of paraffin-embedded rat heart using PAab09856(TYR antibody) at dilution of 1:100
WB use
mouse liver were subjected to SDS PAGE followed by western blot with PAab09856(TYR antibody) at dilution of 1:1000
Protein Information
Gene ID 7299
Uniprot ID P14679
Calculated MW 126 kDa
Research Area Signal Transduction, Metabolism, Cancer
