MX1| MX1 antibody

MX1 antibody

Product Name MX1 antibody

Catalog No PAab09996

Packing 100ul

Form liquid

Alternative Name IFI 78K, IFI78, Interferon induced protein p78, MX, MX1, MxA, Myxovirus resistance protein 1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Immunogen Myxovirus resistance protein 1

Specificity Human, rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500-1:2000; IHC: 1:20-1:200

IHC use Immunohistochemistry of paraffin-embedded rat kidney slide using PAab09996(MX1 Antibody) at dilution of 1:100

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09996(MX1 antibody) at dilution of 1:1000

Protein Information

Gene ID 4599

Uniprot ID P20591

Calculated MW 76 kDa

Research Area Immunology, Signal Transduction