货号 PAab01290
蛋白别名 Active caspase 3 antibody, Apopain antibody, CASP 3 antibody, CASP3 antibody, Caspase 3 antibody, Caspase 3 subunit p17 antibody, Cleaved Caspase 3 antibody, CPP 32 antibody, CPP32 antibody, CPP-32 antibody, CPP32B antibody, Cysteine protease CPP32 antibody, P17 antibody, Protein Yama antibody, SREBP cleavage activity 1
蛋白介绍
Caspase 3, also named as CPP32, SCA-1 and Apopain, belongs to the peptidase C14A family. Caspase 3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase 3 cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. CASP3 is involved in the cleavage of huntingtin. The antibody can recognize p17 of caspase 3 specifically.
产品描述
anti-cleaved-caspase 3 antibody is a Rabbit Polyclonal antibody againstcleaved-caspase 3..建议稀释比例
WB:1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using PAab01290( Caspase 3 Antibody) at dilution of 1:50
Western blot
Tunicamycin treated HeLa cells were subjected to SDS PAGE followed by western blot with PAab01290( Caspase 3 Antibody) at dilution of 1:600(本抗体仅供体外科研用途，不可用于临床诊断!)
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