货号 PAab00345
蛋白别名 Alpha synuclein antibody, NACP antibody, PARK1 antibody, PARK4 antibody, SNCA
蛋白介绍
SNCA, also named as NACP, PARK1 and Alpha-synuclein, belongs to the synuclein family. It may be involved in the regulation of dopamine release and transport. SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. The deposition of aggregated SNCa is the pathological hallmark of Lewy body disease, which includes Parkinson's disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer's disease (LBV).(PMID:21056999) This antibody can recognize all the isoforms of SNCA.
产品描述
anti-alpha-synuclein antibody is a Rabbit Polyclonal antibody againstalpha-synuclein..建议稀释比例
WB :1:500-1:5000;IF:1:10-1:100;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human brain using PAab00345(SNCA antibody) at dilution of 1:50
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab00345(SNCA antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!)
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