Anti–beta Amyloid Rabbit pAb
- 品牌：Servicebio
- 型号：GB11307
- 供应商：武汉赛维尔生物科技有限公司
- 供应商报价：¥650
- 标签：Anti–beta Amyloid Rabbit pAb、Anti–beta Amyloid Rabbit pAb价格、Anti–beta Amyloid Rabbit pAb厂家、、、武汉赛维尔生物科技有限公司
产品库
Product Information
| Description | beta Amyloid rabbit polyclonal |
| Protein full name | Amyloid beta A4 protein |
| Synonyms | APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, amyloid beta precursor protein, preA4 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse APP |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Membrane |
| Uniprot ID | P12023,P08592 |
Applications
| Applications | IHC,IF |
| Species | Mouse,Rat |
| Dilution | 1:500-1:1000 |
| Positive tissue | brain |
Background
Functions as a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis.
Images
 | Immunohistochemistry analysis of paraffin-embedded Rat brain using APP(GB11307) at dilution of 1:500 |
 | Immunohistochemistry analysis of paraffin-embedded mouse brain using APP(GB11307) at dilution of 1:500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
