Anti -Progesterone receptor Rabbit pAb
- 品牌：Servicebio
- 型号：GB11262
- 供应商：武汉赛维尔生物科技有限公司
- 供应商报价：¥650
- 标签：Anti -Progesterone receptor Rabbit pAb、Anti -Progesterone receptor Rabbit pAb价格、Anti -Progesterone receptor Rabbit pAb厂家、、、武汉赛维尔生物科技有限公司
产品库
Product Information
| Description | Progesterone receptor rabbit polyclonal |
| Protein full name | Progesterone receptor |
| Synonyms | PGR, NR3C3, PR, progesterone receptor |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Nucleus,Cytoplasm |
| Uniprot ID | Q00175,Q63449,P06401 |
Applications
| Applications | IHC | ||
| Species | Human,Mouse,Rat | ||
| Dilution | 1:500-1:1000 | ||
| Positive tissue | endometrial cancer,uterus |
Background
Progesterone is necessary to induce the progesterone receptors. When no binding hormone is present the carboxyl terminal inhibits transcription. Binding to a hormone induces a structural change that removes the inhibitory action. Progesterone antagonists prevent the structural reconfiguration. After progesterone binds to the receptor, restructuring with dimerization follows and the complex enters the nucleus and binds to DNA. There transcription takes place, resulting in formation of messenger RNA that is translated by ribosomes to produce specific proteins.
Images
 | Immunohistochemistry analysis of paraffin-embedded human endometrial cancer using Progesterone receptor (GB11262) at dilution of 1:500
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 | Immunohistochemistry analysis of paraffin-embedded human uterus using Progesterone receptor (GB11262) at dilution of 1:500
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 | Immunohistochemistry analysis of paraffin-embedded mouse uterus using Progesterone receptor (GB11262) at dilution of 1:1000
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Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
