品Pai:miltenyi，产品名称：Anti-TCR Vβ5.3-VioBright FITC, human
Anti-TCR Vβ5.3 antibodies, human - Miltenyi Biotec
货号：130-110-141
Clone REA670 recognizes the human variable beta 5.3 subunit of the α/β T cell receptor (TCR Vβ5.3), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.3 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. TCR Vβ5.3 is expressed on a subset of peripheral blood T cells.
Additional information: Clone REA670 displays negligible binding to Fc receptors.
| Clone | Isotype |
|---|---|
| REA670 | recombinant human IgG1 |
