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CD252 funct. grade pure/CD252 (OX40L) antibodies – functional grade, rat

产品信息


  • 品Pai:miltenyi,产品名称:CD252 funct. grade pure, rat
    CD252 (OX40L) antibodies – functional grade, rat - Miltenyi Biotec
    货号:130-104-212
    Clone ATM-2 recognizes the rat CD252 antigen, a member of the TNF ligand superfamily, also known as OX40 ligand (OX40L) or tumor necrosis factor ligand superfamily member 4 (Tnfsf4). CD252 is constitutively expressed by splenic dendritic cells and can be upregulated on splenic B cells via stimulation with LPS. Expression of the cognate receptor CD134 (OX40) is found predominantly on activated T cells. CD252/CD134 interaction promotes the proliferation and survival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells, and inhibits the generation of inducible regulatory T cells.

    Alternative namesTNFSF4, OX40L
    Clone and isotype
    CloneIsotype
    ATM-2mouse IgG1κ

    温馨提示:不可用于临床ZL。
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