Qa-1b funct. grade pure/Anti-QA-1B antibodies – functional grade, mouse

品Pai:miltenyi，产品名称：Anti-Qa-1b funct. grade pure, mouse
Anti-QA-1B antibodies – functional grade, mouse - Miltenyi Biotec
货号：130-104-211
Clone 6A8.6F10.1A6 recognizes murine Qa-1, a 48kDa non-classical MHC class Ib molecule encoded by the H2-T23 gene on chromosome 17. Qa-1 associates with b2-microglobulin and its surface expression is found on activated hematopoietic cells, T cells, DCs, macrophages and neurons. Murine Qa-1 presents a nine amino acid peptide called Qa-1 determinant modifier (Qdm), peptides from proteins associated with infectious or inflammatory response and a heat shock protein 60 (HSP60)-derived peptide (in the absence of Qdm) to immunoregulatory CD8⁺ T cells. Qa-1 also serves as a ligand for C-type lectin CD94/NKG2 receptors and depending on the NKG2 family member involved, this interaction can result in an inhibitory or an activating signal.

Alternative namesH2-T23

Clone and isotype

Clone	Isotype
6A8.6F10.1A6	mouse IgG1