Endonuclease G Antibody

品Pai:CST，产品名称：Endonuclease G Antibody #4969
英文名称：Endonuclease G Antibody
Product name：Endonuclease G Antibody #4969
Source：Rabbit
Sensitivity：Endogenous
MW(kDa)：25, 30
Applications：WB ,
Purification： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Cys122 of human Endonuclease G. Antibodies were purified by protein A and peptide affinity chromatography.
Background： Endonuclease G (EndoG) is a nuclear-encoded mitochondrial nuclease that has been reported to function in apoptosis, DNA recombination and cell proliferation (1-5). EndoG is expressed as a precursor protein containing an amino-terminal mitochondrial targeting sequence which is removed when the protein is imported into the mitochondria (1). During apoptosis EndoG is released from the mitochondria, translocates to the nucleus and cooperates with other nucleases to trigger DNA fragmentation associated with the apoptotic process (3,6,7).

Entrez-Gene Id

2021

Swiss-Prot Acc.

Q14249

Specificity / Sensitivity:

Endonuclease G Antibody detects endogenous levels of total Endonuclease G protein.

Species Reactivity:

Human, Mouse, Rat

Species predicted to react based on sequence homology:

Monkey

Application	Dilutions
Western Blotting	1:1000

Storage:

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.