商品分类：多克隆抗体
靶点/蛋白：Rabbit anti-Endonuclease G antibody recognizes human endonuclease G, also known as endoG. Endo G is a 297 amino acid, including a 48 amino acid transit peptide ~36 kDa mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis.EndoG is reported to act independently of caspases and may represent a caspase independent apoptotic pathway initiated from the mitochondria (Liet al.2001).
来源：Rabbit
参考文献：1. Colado, E.
et al. (2011) Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response.Haematologica. 96: 687-95.1. Li, L.Y.
et al. (2001) Endonuclease G is an apoptotic DNase when released from mitochondria. Nature. 412: 95 - 99.
特异性：Human
别名：Endonuclease G, mitochondrial, Endo G, 3.1.30.-, ENDOG
简单描述：Rabbit Polyclonal Anti-Endonuclease G Antibody . Validated for use in WB, IHC-P.
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
