免疫原: KLH conjugated synthetic peptide derived from human PGC1 alpha + beta
适应物种: 详见说明书
宿主: 详见说明书
标记物: 详见说明书
抗体名: 过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体图片
抗体英文名: Anti-PGC1 alpha + beta
保质期: 详见说明书
抗原来源: Rabbit
克隆性: 多克隆
目录编号: 详见说明书
级别: 详见说明书
靶点: 详见说明书
数量: 大量
供应商: 上海博湖
规格: 0.2ml/200μg
过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体图片突触囊泡融合蛋白Unc18-3抗体 Anti-Unc18-3 WB IHC-P IHC-F IF 100ul 泛素蛋白连接酶E3α2抗体 Anti-UBR2 WB IHC-P IHC-F IF 100ul 肿瘤YZ基因UVRAG抗体 Anti-UVRAG WB IHC-P IHC-F IF 100ul 泛素结合酶UFC1抗体 Anti-UFC1 WB IHC-P IHC-F IF 100ul 泛素结合酶E2J1抗体 Anti-UBE2J1 WB IHC-P IHC-F IF 英文名称 Anti-PGC1 alpha + beta 中文名称过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体图片 别名 LEM6; Ligand effect modulator 6; PERC; Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; Peroxisome proliferative activated receptor, gamma, coactivator 1; Peroxisome proliferator activated receptor gamma coactivator 1 alpha; peroxisome proliferator-activated receptor gamma coactivator 1 beta; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; PGC 1 (alpha); PGC 1 alpha; PGC 1v; PGC-1(beta); PGC-1-alpha; PGC-1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC1; PGC1(alpha); PGC1A; PGC1v; PPAR gamma coactivator 1 alpha; PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6; PPAR gamma coactivator 1; PPAR gamma coactivator variant form; PPAR gamma coactivator-1beta; PPAR-gamma coactivator 1-alpha; PPAR-gamma coactivator 1-beta; PPARGC 1 alpha; PPARGC-1-alpha; PPARGC-1-beta; PPARGC1; PPARGC1A; Ppargc1b; PRGC1_HUMAN; PRGC2_HUMAN. 过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体图片浓度 1mg/1ml 规格 0.1ml/100μg 0.2ml/200μg 抗体来源 Rabbit 克隆类型 polyclonal 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit 产品类型一抗 研究领域心血管细胞生物染色质和核信号信号转导糖尿病表观遗传学 蛋白分子量 predicted molecular weight: 88/113kDa 性状 Lyophilized or Liquid 免疫原 KLH conjugated synthetic peptide derived from human PGC1 alpha + beta 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体图片产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 产品介绍 The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq]. Function : Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Subunit : Binds MYBBP1A, which inhibits transcriptional activation by this protein. Interacts with PRDM16. Interacts with LRPPRC. Homooligomer. Interacts with LPIN1. Subcellular Location : Nucleus. Post-translational modifications : Phosphorylation by AMPK in skeletal muscle increases activation of its own promoter. Phosphorylated by CLK2. Similarity : Contains 1 RRM (RNA recognition motif) domain. Database links : UniProtKB/Swiss-Prot: Q9UBK2