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EGFR Mutant (G719C), Active

产品信息
  • 研究领域：AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, PKA/PKC Pathway, Receptor Tyrosine Kinases,

    靶点/蛋白质：Recombinant human EGFR (G719C) (695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

    来源：Sf9 insect cells using baculovirus

    存储溶液：50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

    参考文献：1. Wang K, et al: Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. J. Biol. Chem. 279: 53848-53856, 2004. 2. Kobayashi S, et al: EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. New Eng. J. Med. 352: 786-792, 2005.

    特异性：Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.

    别名：ERBB, mENA, ERBB1, HER1

    应用：Kinase Assay

    官网链接：https://www.signalchem.com/product_details.php?id=10540

    商品关键词：EGFR Mutant (G719C), Active,E10-12FG-BULK,SignalChem

    简单描述：Recombinant human EGFR (G719C) (695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

    Species: Human

    Tag: GST tag

    Sequence: 695-end (G719C)

    Genbank Number: NM_005228

    Molecular Weight: ~89 kDa


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