Influenza-B Florida

Influenza-B FloridaCATALOGUE NUMBER

IHA-026

INTRODUCTIONInfluenza-B virus is a genus in the virusfamily Orthomyxoviridae. The only species in this genus is called "Influenza B virus". Influenza B virus only infects humansand seals. This limited host range is apparently in contrast with those caused by the similar Influenza virus A as both mutate by both genetic drift and reassortment. Influenza-B virus evolves slower than A viruses and faster than C viruses. Influenza-B virus mutates at a rate 2-3 times lower than type A. However, influenza B mutates enough that lasting immunity is not possible. The Influenza B virus capsidis enveloped while its virionconsists of a matrix protein + envelope + nucleoprotein complex + nucleocapsid, and a polymerasecomplex. Influenza B is sometimes spherical and sometimes filamentous. Its 500 or so surface projections are made of hemagglutinin and neuraminidase.
The Influenza B virus is 14648 nucleotideslong and consists of eight segments of linear negative-sense, single-stranded RNA. The multipartite genome is encapsidated, each segment in a separate nucleocapsid, and the nucleocapsids are surrounded by one envelope.DESCRIPTIONAllantoic fluid of 10 days old embryonated eggs, inoculated with influenza B virus, strain B/Florida/07/04. The Influenza B Virus was purified by Ultracentrifugation with 10-40 % sucrose gradient.INACTIVATIONThimerosal and beta propiolactone treatment
This product has been treated in a manner consistent with methods of inactivation. Generally accepted good laboratory practices appropriate to microbiological/viral safe handling practices and techniques are required at work.PHYSICAL APPEARANCESterile Filtered colorless solution.FORMULATIONThe B/Florida/07/04 solution contains STE, 0.09% sodium azide (NaN₃) and 0.005% thimerosal.STABILITYB/Florida/07/04 although stable 4°C for 4 weeks, should be stored below -18°C. 
Please prevent freeze-thaw cycles.IMMUNOLOGICAL ACTIVITYTested with anti-influenza B monoclonal antibodies in ELISA.Serological studies of influenza B virus, immunogen for antibody production.PURITYGreater than 90.0% as determined by SDS-PAGE.USAGEProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.