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Alpha-synuclein Antibody (internal region) | LBP77169 | Leading Biology

产品信息
  • 商品分类:多克隆抗体

    产品概述:This antibody is expected to recognize both reported isoforms (NP_009292.1; NP_000336.1). Reported variants represent identical protein: NP_000336.1, NP_001139527.1, NP_001139526.1

    来源:Goat

    存储溶液:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

    参考文献:Mimicking phosphorylation at serine 87 inhibits the aggregation of human ?-synuclein and protects against its toxicity in a rat model of Parkinson's disease. Oueslati A, Paleologou KE, Schneider BL, Aebischer P, Lashuel HA. J Neurosci. 2012 Feb 1;32(5):1536-44. PMID: 22302797

    特异性:Human, Mouse

    别名:Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, SNCA, NACP, PARK1

    简单描述:Goat Polyclonal Alpha-synuclein Antibody (internal region). Validated for use in WB, E.

    详情:FunctionMay be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.Cellular_LocationCytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neuronsTissue_LocationExpressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals

    生物商城:http://www.annoron.com

    办公电话:010-56256916

    官方售后:400-965-8633

    企业 QQ:3212874516、3198592576

    地 址:北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
    温馨提示:不可用于临床ZL。
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