商品分类:多克隆抗体
产品概述:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
靶点/蛋白:Recognizes 14-3-3 eta in all mammals. It is a member of the 14-3-3 family which consists of 30 kD proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, ...
来源:Rabbit
参考文献:Swanson K.D.,et al.Biochim. Biophys. Acta 1216:145-148(1993).Ichimura-Ohshima Y.,et al.J. Neurosci. Res. 31:600-605(1992).Leffers H.,et al.Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.Muratake T.,et al.Mol. Neurobiol. 11:223-230(1995).Muratake T.,et al.Genomics 36:63-69(1996).
特异性:Human, Mouse, Rat, Rabbit, Chicken, Sheep, Bovine
别名:14-3-3 protein eta, Protein AS1, YWHAH, YWHA1
应用:IHC-P (1:250)
简单描述:Rabbit Polyclonal YWHAH / 14-3-3 Eta Antibody (N-Terminus). Validated for use in WB, IHC-P.
详情:FunctionAdapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.Tissue_LocationExpressed mainly in the brain and present in other tissues albeit at lower levels
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