商品分类:多克隆抗体
产品概述:Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
靶点/蛋白:Human DAX1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
来源:Rabbit
参考文献:Zanaria E.,et al.Nature 372:635-641(1994).Guo W.,et al.J. Clin. Endocrinol. Metab. 81:2481-2486(1996).Altincicek B.,et al.J. Biol. Chem. 275:7662-7667(2000).Suzuki T.,et al.Mol. Cell. Biol. 23:238-249(2003).Ho J.,et al.Mol. Genet. Metab. 83:330-336(2004).
特异性:Human
别名:Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, NR0B1, AHC, DAX1
应用:IHC-P (10 μg/ml)
简单描述:Rabbit Polyclonal NR0B1 / DAX1 Antibody (Ligand-binding Domain). Validated for use in IHC-P.
详情:FunctionOrphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).Cellular_LocationNucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus
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