商品分类：多克隆抗体
产品概述：Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1- acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.
靶点/蛋白：Human PLA1A. At least three isoforms of PLA1A are known to exist; this antibody will detect all three isoforms.
来源：Rabbit
参考文献：van Groningen J.J.M.,et al.FEBS Lett. 404:82-86(1997).Nagai Y.,et al.J. Biol. Chem. 274:11053-11059(1999).Ota T.,et al.Nat. Genet. 36:40-45(2004).Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.Muzny D.M.,et al.Nature 440:1194-1198(2006).
特异性：Human, Rat
别名：Phospholipase A1 member A, 3.1.1.-, Phosphatidylserine-specific phospholipase A1, PS-PLA1, PLA1A, NMD, PSPLA1
应用：IF (20 μg/ml), IHC-P (10 μg/ml), WB (1-2 μg/ml)
简单描述：Rabbit Polyclonal PSPLA1 / Phospholipase A1 Antibody (C-Terminus). Validated for use in WB, IHC-P, IF, E.
详情：FunctionHydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1- acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.Cellular_LocationSecreted.Tissue_LocationWidely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
