商品分类：多克隆抗体
产品概述：The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
来源：Goat
存储溶液：0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
参考文献：Polymorphic variants of genes related to arginine metabolism and the risk of orofacial clefts. Hozyasz KK, et al. Arch Oral Biol, 2010 Aug 23. PMID 20739017.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Reduced argininosuccinate synthetase is a predictive biomarker for the development of pulmonary metastasis in patients with osteosarcoma. Kobayashi E, et al. Mol Cancer Ther, 2010 Mar. PMID 20159990.Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4. Tsai WB, et al. Mol Cancer Ther, 2009 Dec. PMID 19934275.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
特异性：Human, Cow
别名：Argininosuccinate synthase, 6.3.4.5, Citrulline--aspartate ligase, ASS1, ASS
简单描述：Goat Polyclonal Goat Anti-Argininosuccinate synthetase 1 Antibody. Validated for use in WB, IHC, IF, IP, E.
详情：FunctionIs indirectly involved in the control of blood pressure.
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
