Ceramide Kinase / CERK Antibody (Internal) | LBP66362 | Leading Biology

商品分类：多克隆抗体

产品概述：Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

靶点/蛋白：Human CERK. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

来源：Rabbit

参考文献：Sugiura M.,et al.J. Biol. Chem. 277:23294-23300(2002).Van Veldhoven P.P.,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).Ota T.,et al.Nat. Genet. 36:40-45(2004).Dunham I.,et al.Nature 402:489-495(1999).

特异性：Human, Monkey

别名：Ceramide kinase, hCERK, 2.7.1.138, Acylsphingosine kinase, Lipid kinase 4, LK4, CERK, KIAA1646

应用：IHC-P (20 μg/ml)

简单描述：Rabbit Polyclonal Ceramide Kinase / CERK Antibody (Internal). Validated for use in IHC-P.

详情：FunctionCatalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.Cellular_LocationCytoplasm. Membrane; Peripheral membrane proteinTissue_LocationHigh level expression in heart, brain, skeletal muscle, kidney and liver; moderate in peripheral blood leukocytes and thymus; very low in spleen, small intestine, placenta and lung

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