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Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody | LM19746 | Leading Biology

产品信息
  • 商品分类:单克隆抗体

    产品概述:This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

    来源:Mouse

    参考文献:Woodock-Mitchell J et. al. Journal of Cell Biology 1982;95:580-8. | Tseng SCG et. al. Cell 1982; 30361. |

    特异性:Human, Mouse, Rat, Rabbit, Monkey, Chicken, Cow, Dog

    别名:Keratin, type II cytoskeletal 2 oral, Cytokeratin-2P, CK-2P, K2P, Keratin-76, K76, Type-II keratin Kb9, KRT76, KRT2B, KRT2P

    简单描述:Mouse Monoclonal Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody. Validated for use in WB, IHC, IF, FC. Clone: AE-3.

    详情:FunctionProbably contributes to terminal cornification.

    生物商城:http://www.annoron.com

    办公电话:010-56256916

    官方售后:400-965-8633

    企业 QQ:3212874516、3198592576

    地 址:北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
    温馨提示:不可用于临床ZL。
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