商品分类：单克隆抗体
产品概述：General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
靶点/蛋白：TBP
来源：Mouse
参考文献：Hoffmann A.,et al.Nature 346:387-390(1990).Peterson M.G.,et al.Science 248:1625-1630(1990).Kao C.C.,et al.Science 248:1646-1650(1990).Ota T.,et al.Nat. Genet. 36:40-45(2004).Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
特异性：Human, Mouse
别名：TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit, TBP, GTF2D1, TF2D, TFIID
简单描述：Mouse Monoclonal TBP monoclonal antibody. Validated for use in WB. Clone: .
详情：FunctionGeneral transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.Cellular_LocationNucleus.Tissue_LocationWidely expressed, with levels highest in the testis and ovary.
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
