商品分类：单克隆抗体
靶点/蛋白：Mouse anti-Human Myeloperoxidase antibody, clone 2C7 recognizes human myeloperoxidase (MPO). MPO is an important component of azurophilic granules in neutrophils, being involved in microbicidal processes. The protein is a multimer of 2 heavy chains (55kD) and two light chains (15kD), the heavy chains being linked by a disulphide bond. Mouse anti-Human Myeloperoxidase antibody, clone 2C7 recognizes native MPO in Western blots, and the heavy chain following boiling of the sample. Mouse anti-Human Myeloperoxidase antibody, clone 2C7 also recognizes recombinant MPO in Western blots and weakly in ELISA.Mouse anti-Human Myeloperoxidase antibody, clone 2C7 may be of value in the study of myeloid cells and myeloid leukaemias by flow cytometry following cell permeablisation.
来源：Mouse
参考文献：1. Audrain, M.A.P.
et al. (1997) Anti-native and recombinant myeloperoxidase monoclonals and human autoantibodies.Clin. Exp. Immunol. 107: 127-134. 2. Patry, Y.C.
et al. (1997) Difference in antigenic determinant profiles between human and rat myeloperoxidase.Clin ExpImmunol. 132: 505-8. 3. Zhang, N.
et al. (2008) Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease.J Allergy Clin Immunol. 122: 961-8. 4. Sloane, A.J.
et al. (2005) Proteomic analysis of sputum from adults and children with cystic fibrosis and from control subjects.Am J Respir Crit Care Med. 172: 1416-26. 5. Luo, B.
et al. (2013) Immunopathology features of chronic rhinosinusitis in high-altitude dwelling Tibetans.Allergy Rhinol (Providence). 4: e69-76. 6. Behnen, M.
et al. (2014) Immobilized immune complexes induce neutrophil extracellular trap release by human neutrophil granulocytes via Fc?RIIIB and Mac-1.J Immunol. 193 (4): 1954-65. 7. Villiers, E.
et al. (2006) Identification of acute myeloid leukemia in dogs using flow cytometry with myeloperoxidase, MAC387, and a canine neutrophil-specific antibody.Vet Clin Pathol. 35 (1): 55-71.
特异性：Human
别名：Myeloperoxidase, MPO, 1.11.2.2, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO
简单描述：Mouse Monoclonal Anti-Human Myeloperoxidase Antibody, clone 2C7 (RPE). Validated for use in WB, IHC-P, IHC-F, FC, E. Clone: 2C7.
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
