商品分类:单克隆抗体
产品概述:Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
来源:Mouse
存储溶液:200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
参考文献:Hogg N, et. al. European Journal of Immunology, 1984, 14:236-43
特异性:Human, Baboon, Rhesus, Cynomolgus Monkey
别名:Complement receptor type 1, C3b/C4b receptor, CD35, CR1, C3BR
简单描述:Mouse Monoclonal CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody - Without BSA and Azide. Validated for use in IHC-P, IF, FC. Clone: E11.
详情:FunctionMediates cellular binding of particles and immune complexes that have activated complement.Cellular_LocationMembrane; Single-pass type I membrane proteinTissue_LocationPresent on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells
生物商城:http://www.annoron.com
办公电话:010-56256916
官方售后:400-965-8633
企业 QQ:3212874516、3198592576
地 址:北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示:不可用于临床ZL。