商品分类：单克隆抗体
产品概述：This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.
来源：Mouse
参考文献：Sato T et al. Blood 94:2548-2554 (1999). | Felshow DM et al. Blood 97:3768-3775 (2001). |
特异性：Human
别名：Hematopoietic progenitor cell antigen CD34, CD34, CD34
简单描述：Mouse Monoclonal CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody - Without BSA. Validated for use in IHC, IF, FC. Clone: HPCA1/763.
详情：FunctionPossible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.Cellular_LocationMembrane; Single-pass type I membrane proteinTissue_LocationSelectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
