商品分类：单克隆抗体
产品概述：Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
来源：Mouse
参考文献：Kishimoto T et al. (eds) Leukocyte Typing VI. P67-71, Garland Publishing, New York, 1997
特异性：Human
别名：CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
简单描述：Mouse Monoclonal CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody - Without BSA and Azide. Validated for use in IF, FC. Clone: 203.6.
详情：FunctionReceptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.Cellular_LocationMembrane; Single-pass type I membrane proteinTissue_LocationFound in most T-lymphocytes.
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示：不可用于临床ZL。
