c-erbB-2 Human

c-erbB-2 HumanCATALOGUE NUMBER

PKA-340

SYNONYMSReceptor tyrosine-protein kinase erbB-2, EC 2.7.10.1, p185erbB2, C-erbB-2, NEU proto-oncogene, Tyrosine kinase-type cell surface receptor HER2, MLN 19, CD340 antigen, NEU, NGL, HER2, TKR1, HER-2, c-erb B2, HER-2/neu.INTRODUCTIONc-erbB-2 is a receptor tyrosine kinase of the c-erbB family. It is closely related instructure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.DESCRIPTIONc-erbB-2 Human Recombinant encoding 537-636 amino acids expressed in E.coli, shows a 37kDa band on SDS-PAGE.
c-erbB-2 is purified by proprietary chromatographic techniques.SOURCEEscherichia Coli.PHYSICAL APPEARANCESterile Filtered clear solution.FORMULATIONc-erbB2 at 100 µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.STABILITYStore vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. 
Please avoid freeze-thaw cycles.USAGEProspec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.