重组人结核分枝杆菌热休克蛋白65/HSP65 Mycobacterium
- 产地：福建 厦门市
- 供应商：厦门慧嘉生物科技有限公司
- 供应商报价： 电议
- 标签：重组人结核分枝杆菌热休克蛋白65/HSP65 Mycobacterium,重组人结核分枝杆菌热休克蛋白65/HSP65 Mycobacterium价格,重组人结核分枝杆菌热休克蛋白65/HSP65 Mycobacterium厂家
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| Catalogue Number | HSP-065 |
| Synonyms | Protein Cpn60-2, groEL protein-2, 65 kDa antigen, Heat shock protein 65, Cell wall protein A, Antigen A, groL2, groEL-2. |
| Introduction | Heat shock proteins induce pro-inflammatory cytokines. Mycobacterial HSPs participate in cytokine expression resulting from infection by M. tuberculosis. Furthermore, HSPs stabilize cellular proteins in response to various sources of stress or injury. HSP65 is one of the most essential defending immunogens against the tuberculosis infection. HSP65 is presented to human CD41 T cells in association with multiple HLA-DR molecules. The M. tuberculosis HSP65 signals through TLR4. |
| Description | Recombinant Mycobacterium Tuberculosis HSP65 is produced in E.coli and has a Mw of 57.4 kDa. The HSP65 protein is fused to His-Tag at N-Terminus and purified by stabdard chromatography techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | The HSP65 protein was lyophilized from a concentrated (1mg/ml) solution containing 10mM Na-phosphate pH-7.4, 130mM NaCl and 2.5mM KCl. |
| Solubility | It is recommended to reconstitute the lyophilized HSP-65 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized HSP65 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HSP65 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Amino Acid Sequence | HHHHHHGSAKTIAYDEEARRGLERGLNALADAVKV TLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPY EKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVRE GLRNVAAGANPLGLKRGIEAVEKVTETLLKGAKEVET KEQIAATAAISAGDQSIGDLIAEAMDKVGNEGVITV EESNTFGLQLELTEGMRFDKGYISGYFVTDPERQEAV LEDPYILLVSSKVSTVKDLLPLLEKVIGAGKPLLIIEDVEGE ALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAIL TGGQVISEEVGLTLENADLSLLGKARKVVVTKDETTIVE GAGDTDAIAGRVAQIRQEIENSDSDYDREKLQERLAKL AGGVAVKAGAATEVELKERKHRIEDAVRNAKAAVEEGIV AGGGVTLLQAAPTLDELKLEGDEATGANIVKVALEAPL KQIAFNSGLEPGVVAEKVRNLPAGHGLNAQTGVYEDLLA AGVADPVKVTRSALQNASIAGLFLTTEAVVADKPEKEKASVPGGGDMGGMDF. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
