人类的炎症反应和自身免疫甲基化PCR芯片 Inflammatory Response & Autoimmunity EpiTect Methyl qPCR Array

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Inflammatory Response & Autoimmunity EpiTect Methyl qPCR Array

人类的炎症反应和自身免疫甲基化PCR芯片
 

Product	Species	Technology	Cat. No.
Inflammatory Response & Autoimmunity EpiTect Methyl qPCR Array	Human	DNA Methylation	EAHS-521Z
Inflammatory Response & Autoimmunity EpiTect Methyl qPCR Array	Mouse	DNA Methylation	EAMM-521Z
Inflammatory Response & Autoimmunity EpiTect Methyl qPCR Array	Rat	DNA Methylation	EARN-521Z

The Human Inflammatory Response & Autoimmunity EpiTect Methyl II Signature PCR Array profiles the promoter methylation status of a panel of 22 genes whose involvement in inflammation has been well documented. Profiling cellular or fresh tissue DNA samples with these arrays may help correlate CpG island methylation status with anti- or pro-inflammatory responses. The results may also help provide insights into the molecular mechanisms and biological pathways behind inflammatory disease. With a simple restriction enzyme digestion and real-time PCR, research studies can analyze the promoter methylation status of 22 different inflammatory response and autoimmunity genes with this DNA methylation PCR array.
Both 96-well and 384-well ( 4 X 96 ) formats are available.
The EpiTect Methyl II PCR Arrays use the MethylScreen™ Technology provided under license from Orion Genomics, LLC
人类的炎症反应和自身免疫甲基化PCR芯片用于研究已报道参与炎症反应的22个关键基因的启动子甲基化状态。利用该芯片分析细胞或新鲜组织DNA样本可能有助于研究CpG岛甲基化状态与促炎或KY反应的关系。结果也可能助于洞察炎性疾病背后的分子机制和生物学通路。利用这个芯片，通过简单的限制性内切酶消化和实时定量PCR，就可以研究分析22个不同炎症反应与自身免疫基因的启动子甲基化状态。
包括96-孔板和384-孔板( 4 X 96 )。
 
Chemokines: CCL25, CXCL14, CXCL3, CXCL5, CXCL6.
Cytokines: IL12A, IL12B, IL17C, INHA.
Cytokine Receptors & Associated Proteins: IL10RA, IL12B, IL13RA1, IL15, IL17RA, IL4R, IL6R, IL6ST.
Other Inflammatory Response & Autoimmunity Genes: ATF2, FADD, GATA3, IL13, IL7, TYK2.