Stemgent® DyLight™488 Rabbit anti-Human/Mouse Oct4 Antibody详细信息：
Product Overview
DylightTM 488 Rabbit anti-Human/Mouse Oct-4 Monoclonal Antibody (clone # C30A3). Oct-4 (Octamer-4) is a homeodomain transcription factor of the POU family (POU5F1) involved in regulation of pluripotency during normal development and is detectable in embryonic stem (ES) and germ cells. Its expression is associated with an undifferentiated phenotype and tumors. In fact, gene knockdown of Oct4 promotes differentiation, thereby demonstrating a role for this factor in human ES cell self-renewal. As such, it is frequently used as a marker for undifferentiated ES cells or iPS (induced pluripotent stem) cells. Oct4 is one of the four key transcription factors (Oct4, Sox2, c-Myc, and KLF4) used to reprogram mouse and human fibroblasts to a pluripotent state as well as generate patient-specific iPS cells(1-5).
Stemgent® DyLight™488 Rabbit anti-Human/Mouse Oct4 AntibodyProduct Specifications
Size / Quantity 50 µg (116 µl at 0.43 mg/ml)
Immunogen Recombinant protein specific to the amino terminus of human Oct4
Reactivity Human, Mouse
Clone C30A3
Isotype Rabbit IgG
Formulation Phosphate-buffered solution pH 7.2 containing ≤0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with DyLight™ 488 under optimal conditions. The stock solution is free of unconjugated dye and free antibody.
Stemgent® DyLight™488 Rabbit anti-Human/Mouse Oct4 AntibodyStorage Store undiluted at 4°C. Do not freeze. Light sensitive.
Stability Stable for 6 months from date of receipt when stored as directed.
Quality Control Tested by immunocytochemistry (Figure 1) and flow cytometry (Figure 2).
Recommended Usage Dilute 1:100 for immunocytochemistry applications and 1:5 for flow cytometry applications.
Related Products
Stemgent® Affinity Purified anti-Mouse/Human Oct4 Antibody (Cat. # 09-0023)
Notice to Purchaser Purchaser represents and warrants that it will use Stemgent® Dylight™488 Rabbit anti-Human/Mouse Oct4 Antibody purely for research purposes, not for diagnostic use, not for resale, and not for use in humans or veterinary applications. Stemgent will not be held responsible for patent infringement or other violations that may occur with the use of our products.
Trademark DyLight™ is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
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