Human Serum & Plasma 384HC miRNA PCR Array: MIHS-3106Z
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The Human Serum & Plasma 384HC miScript miRNA PCR Array profiles the expression of 372 miRNAs detectable in serum and plasma using the miScript PCR System. This high-content array also includes the 84 miRNAs detectable and differentially expressed in serum, plasma, and other bodily fluids that are found on the Human Serum & Plasma miScript miRNA PCR Array. The serum and plasma 384HC array provides disease and toxicology researchers with a convenient way to quickly analyze the extracellular, circulating miRNAs most relevant to pathophysiological conditions. The discovery of miRNAs in serum and plasma, and their apparently regulated levels there, suggest a mechanistic role for these master regulatory molecules in both normal and pathophysiological processes. Their presence in serum and plasma samples provides readily available source material for research purposes. The profiling results from this array can potentially serve as a useful molecular marker for heart and liver injury or disease, atherosclerosis, diabetes, and a number of organ-specific cancers. This array can also be used with miRNeasy Serum/Plasma Spike-In Control (catalog number 219610). When spiked into the sample before nucleic acid isolation and detected with the control assay, it provides a more useful normalization method for this application than the typical reference short noncoding RNAs, which are not normally detected in serum. A set of controls present on this array enables data analysis using the ΔΔCT method of relative quantification, assessment of reverse transcription performance, and assessment of PCR performance. Using SYBR Green-based real-time PCR, the expression of a focused panel of miRNAs found in serum and plasma can be easily and reliably analyzed with this miScript miRNA PCR Array. miScript miRNA PCR Arrays are intended for molecular biology applications. This product is not intended for the diagnosis, prevention or treatment of a disease |
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