Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain
fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It
binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170.
Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and
also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.
Product Info
Amount : 25 μg / 100 μg
Purification : Protein G Chromatography
Content :
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium
azide is highly toxic.
Storage condition :
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid
repeated freeze and thaw cycles.
