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 干细胞全长重组蛋白0044-ACAT1RecombinantProtein(P01)

产品信息
  • Gene Information

     
    Gene Name:
    ACAT1 
    Related Disease:
    bioinformation not available

    Gene Pathway
    Valine, leucine and isoleucine degradation
    Fatty acid metabolism
    Propanoate metabolism
    Butanoate metabolism
    Tryptophan metabolism
    Benzoate degradation via CoA ligation
    Synthesis and degradation of ketone bodies
    Pyruvate metabolism
    Lysine degradation

     
    Gene Description:
    acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
     
     
    Gene Alias:
    ACAT, MAT, T2, THIL 
     
    Entrez GeneID:
    38 
     
    Omim ID:
    203750 607809
     
     
    Protein Accession#:
    AAH10942 
     
    Gene Ontology:
    Hyperlink 
     

    This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. This gene spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

     Product Information

     
    Product Description:
    ACAT1( AAH10942, 16 a.a. - 163 a.a.) full-length recombinant protein with GST.
     
    Molecular Weight:
    42.28 kDa
       
     
    Polypeptide Chain:
    Human ACAT1
       
     
    Length with Tag:
    381 aa with GST tag
       
     
    Storage Buffer:
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
       
    Storage Instruction:
    Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
      
    Quality Control Testing:
    12.5% SDS-PAGE Stained with Coomassie Blue
      
    Note:Best use within one month from the date of receipt of this protein.
    温馨提示:不可用于临床ZL。
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