Anti-phospho-MBP(Tyr203)磷酸化髓鞘碱性蛋白抗体

本公司经销phospho-MBP（Tyr203），磷酸化髓鞘碱性蛋白抗体，克隆类型为polyclonal，宿主来源是Rabbit，phospho-MBP（Tyr203）磷酸化髓鞘碱性蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-5475R
英文名称：Anti-phospho-MBP（Tyr203）
中文名称：磷酸化髓鞘碱性蛋白抗体
其他名称：名MBP（phospho Y203）; Myelin basic protien; GDB; Golli MBP; Hemopoietic MBP; HMBPR; HUGO; MBP; MGC99675; MLD; Myelin A1 Protein; Myelin Deficient; Myelin Membrane Encephalitogenic Protein; SHI; Shiverer; SP.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 33kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, dog
产品介绍：Oligodendrocyte Marker The classic group of Myelin basic protein （MBP） isoforms （isoforms 4 to 14） are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation ａnd stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms （isoforms 1 to 3/Golli MBPs） may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, ａnd may also be involved in signaling pathways in T cells ａnd neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.Subunit : Homodimer. Isoform 3 exists as a homodimer.Subcellular Location : Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.Tissue Specificity : MBP isoforms are found in both the central ａnd the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen ａnd spinal cord, as well as in cell lines derived from the immune system.Similarity : Belongs to the myelin basic protein family.少突胶质细胞标志物。 主要用于脊髓脱髓鞘病-脊髓多发硬化症的研究。 MBP髓鞘碱性蛋白和髓鞘相伴糖蛋白是多发性硬化的自身免疫攻击的靶。