human Fibrinogen Monoclonal人纤维蛋白原单克隆抗体

本公司经销human Fibrinogen Monoclonal，人纤维蛋白原单克隆抗体，克隆类型为monoclonal，宿主来源是Mouse，human Fibrinogen Monoclonal人纤维蛋白原单克隆抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BYm-1240M
英文名称：Anti-human Fibrinogen Monoclonal
中文名称：人纤维蛋白原单克隆抗体
其他名称：名FGA; FGA protein; FGB; FGG; Fib2; Fibrinogen A alpha polypeptide; Fibrinogen A alpha polypeptide chain; Fibrinogen alpha chain; Fibrinogen B alpha polypeptide; Fibrinogen beta chain; Fibrinogen G alpha polypeptide; Fibrinogen gamma chain; MGC104327; MGC119422; MGC119423; MGC119425; MGC120405.
抗体来源：Mouse
克隆类型：monoclonal
蛋白分子量：predicted molecular weight: 340kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Fibrinogen is the main protein of blood coagulation system. It is a large protein ａnd it consists of two identical subunits that contain three polypeptide chains: alpha, beta ａnd gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A （1 to 16 amino acids） ａnd B （1 to 17 amino acids） are released by thrombin from the N terminal parts of alpha ａnd beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism ａnd thromboses of arteries ａnd veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth ａnd many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient＇s blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease （Sonel A. et al, ａnd Rapold H.J. et al）. All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.产品图片Antigen: bs-1240P 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Mouse IgG（bs-0296G-HRP） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.