Peprotech Recombinant Human IL-2 厂家
Catalog Number:
AF-200-02
Synonyms:
T-cell growth factor （TCGF）, Aldesleukin
Description:
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation ａnd other fundamental functions which are essential for the immune response. IL-2 stimulates growth ａnd differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages ａnd oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.Manufactured using all non-animal reagents.
AA Sequence:
MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Cross Reactivity:
Bacteria, Cow, Dog, Human, Monkey, Mouse, Rat, Leech, Human + Mouse, Cow + Mouse
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