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重组人血小板生长因子-A/PDGF A Human

产品信息
重组人血小板生长因子-A/PDGF A Human
产品编号：CYT-491 
产品规格：5μg/20μg/1mg
Catalogue NumberCYT-491
SynonymsGlioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-A, PDGF-1.
IntroductionThe term ‘PDGF’ refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets.

They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family – PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist – a short form that is soluble and a long form that is retained by the extracellular matrix.
DescriptionPlatelet-Derived Growth Factor A Human Recombinant short chain produced in E.Coli is a non-glycosylated, polypeptide chain containing 110 amino acids fragment (87-196) and having a total Mw of 17.02kDa, with an amino-terminal hexahistidine tag. 

PDGF-A is purified by proprietary chromatographic techniques.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationPlatelet-derived Growth Factor A is supplied in 25mM Na-Acetate, pH-4.8, 1mM EDTA and 50% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. 

Store, frozen at -20°C for longer periods of time. 

Please avoid freeze thaw cycles.
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.



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