人醋酸亮内瑞林/Leuprorelin Human
- 产地:福建 厦门市
- 供应商:厦门慧嘉生物科技有限公司
- 供应商报价: 电议
- 标签:人醋酸亮内瑞林/Leuprorelin Human,人醋酸亮内瑞林/Leuprorelin Human价格,人醋酸亮内瑞林/Leuprorelin Human厂家
Catalogue Number | HOR-260 |
Synonyms | Leuprolide, Leuprorelin. |
Introduction | Leuprorelin (INN) or leuprolide acetate (USAN) is a gonadotropin-releasing hormone agonist (GnRH agonist). By causing constant stimulation of the pituitaryGnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone(LH) and follicle-stimulating hormone(FSH). like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer, estrogen-dependent conditions (such as endometriosisor uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF. |
De | Leuprolide Human Synthetic is a single, non-glycosylated, polypeptide chain containing 9 amino acids and having a molecular mass of 1209 Dalton. The molecular formula is C59H84N16O12. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | The Leuprorelin was lyophilized from a concentrated (1 mg/ml) solution with no additives. |
Solubility | It is recommended to reconstitute the lyophilized Leoprolide in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Stability | Lyophilized Leoprolide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Leuprorelin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Purity | Greater than 98.0% as determined by RP-HPLC. |
Amino acid sequence | pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt. |
Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |