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重组人内皮分化相关因子1/EDF1 Human

产品信息
重组人内皮分化相关因子1/EDF1 Human
产品编号:PRO-494
产品规格:5μg/25μg/1mg
Catalogue NumberPRO-494
Synonyms EDF-1, MBF1, Multiprotein-bridging factor 1.
Introduction EDF1 controls endothelial cell differentiation. EDF1 has a role as a bridging protein that interconnects regulatory proteins and the basal transcriptional machinery, thus modulating the transcription of genes that take part in endothelial differentiation. EDF1 binds calmodulin through its IQ domain and controls nitric oxide synthase activity via calmodulin sequestration in the cytoplasm. EDF1 is localized in adult liver, heart, adipose tissues, intestine and pancreas.
Description EDF1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 156 amino acids (1-148 a.a.) and having a molecular mass of 17.4 kDa. The EDF1 is fused to 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearence Sterile filtered colorless solution.
Formulation 0.5 mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.1M NaCl & 10% glycerol.
Stability EDF1 Human although stable at 4C for 1 week, should be stored desiccated

below -18C. Please prevent freeze thaw cycles.
Purity Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence MAESDWDTVT VLRKKGPTAA QAKSKQAILA AQRRGEDVET SKKWAAGQNK QHSITKNTAK LDRETEELHH DRVTLEVGKV IQQGRQSKGL TQKDLATKIN EKPQVIADYE SGRAIPNNQV LGKIERAIGL KLRGKDIGKP IEKGPRAKLE HHHHHH.
Usage ProSpec''s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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