重组艾滋病毒1 pol整合酶/HIV-1 Integrase
- 产地：福建 厦门市
- 供应商：厦门慧嘉生物科技有限公司
- 供应商报价： 电议
- 标签：重组艾滋病毒1 pol整合酶/HIV-1 Integrase,重组艾滋病毒1 pol整合酶/HIV-1 Integrase价格,重组艾滋病毒1 pol整合酶/HIV-1 Integrase厂家
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| Catalogue Number | HIV-122 |
| Introduction | Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization, a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally, several host cellular proteins interact with integrase and may facilitate the integration process. |
| De | The E.coli derived 36 kDa recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the pol protein (intergrase) and fused with a six histidines tag. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile filtered colorless clear solution. |
| Formulation | 1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X & 50% Glycerol. |
| Purity | Greater than 95.0% as determined by HPLC analysis and SDS-PAGE. |
| Stability | HIV-1 Integrase although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Specificity | Immunoreactive with all sera of HIV-1 infected individuals. |
| Applications | HIV-1 Integrase antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems. |
| Amino Acid Sequence | mfldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlkgea |
| Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
