Human TRAIL/Apo2L/重组人Human TRAIL/Apo2L

Human TRAIL/Apo2L/重组人Human TRAIL/Apo2L
产品编号：100-301
产品规格：50μg
Description: TRAIL/Apo2L is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic ?death domain?, which activates the cell's apoptotic machinery. Recombinant human soluble TRAIL/Apo2L is a 168 amino acid polypeptide (19.6 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL/Apo2L protein.
Source: E. coli
Molecular Weight: 19.6 kDa
Purity: > 98% by SDS-PAGE ans HPLC analysis
Endotoxin level/内毒素水平: < 0.1 ng per μg of TRAIL/Apo2L
Stabilizer: none
Formulation: lyophilized
Biological Activity: Determined by its ability to induce apoptotic cell death in TRAIL-sensitive U343MG cells. The expected for this effect is 1.0-3.0 ng/ml.
Reconstitution: The human TRAIL/Apo2L should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted human TRAIL/Apo2L should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Usage: Human TRAIL/Apo2L offered for research use. Not for drug use. Not for human use.